Effects of reduced glutathione therapy on chronic hepatitis B

Effects of reduced glutathione therapy on chronic hepatitis B

Developed chronic hepatitis B (CHB) causes death in approximately one million patients every year. Therefore, natural drugs with high therapeutic efficacy and minimal side effects must be developed for CHB treatment. This study aimed to relate the therapeutic effects of glutathione on CHB. A total of 104 CHB patients were randomly divided into two groups: the control group, which received an in...

Surface protein mutations in chronic hepatitis B patients who received hepatitis B vaccine therapy

Objective (s):The aim of this study was to determine the correlation between vaccine therapy and appearance of mutations in hepatitis B surface antigen (HBsAg)-positive chronic hepatitis B virus (HBV) patients. Materials and Methods: 16 patients received the HBV vaccine and another 16 individuals from the control group did not. The surface gene was amplified and directly sequenced from samples...

The Effect of Entecavir Therapy on Immune Status in Chronic Hepatitis B Patients

Adverse effects of oral antiviral therapy in chronic hepatitis B

Oral nucleoside/nucleotide analogues (NAs) are currently the backbone of chronic hepatitis B (CHB) infection treatment. They are generally well-tolerated by patients and safe to use. To date, a significant number of patients have been treated with NAs. Safety data has accumulated over the years. The aim of this article is to review and update the adverse effects of oral NAs. NAs can cause class...

Treatment of Chronic Hepatitis B with Tenofovir

Background:Tenofovir is among the first-line treatments for chronic hepatitis B (CHB) virus infection. We evaluated the efficacy of Tenofovir in the treatment of Iranian adult patients with CHB. Methods: In a retrospective study, we evaluated 154 HBsAg positive patients referred to Sadoughi hospital in Yazd-Iran for treatment ...